psc
mobag
jama
psc
nbme

2025

* Bao, J., Wen, J., Chang C., Mu S., Chen J., Shivakumar M., Cui Y., Erus G., Yang Z., Yang S., Wen Z., Zhao Y., Kim D., Duong-Tran D., Saykin A., Zhao Z., Davatzikos C., Long Q., Shen L. (2025). A genetically informed brain atlas for enhancing brain imaging genomics. Nature Communications (in press), Link

* Chen, J., Ionita, M., Feng, Y., Lu, Y., Orzechowski, P., Garai, S., Hassinger, K., Bao, J., Wen, J., Duong-Tran, D. and Wagenaar, J., (2025). Automated cytometric gating with human-level performance using bivariate segmentation. Nature Communications, Link

* Wen, J., (2025). Multi-organ and Multi-omics Aging Clocks Digitize Human Biological Age. medRxiv, Link

* Boquet-Pujadas, A., Anagnostakis, F., Duggan, M.R., Joynes, C.M., Toga, A.W., Yang, Z., Walker, K.A., Davatzikos, C., the MULTI consortium, and Wen, J., (2025). Brain-heart-eye axis revealed by multi-organ imaging genetics and proteomics. medRxiv, Link

* Boquet-Pujadas, A., Zeng, J., Tian, Y.E., Yang, Z., Shen, L., Zalesky, A., Davatzikos, C., the MULTI consortium, and Wen, J., 2025. MUTATE: A Human Genetic Atlas of Multi-organ AI Endophenotypes using GWAS Summary Statistics. pp.2024-06. Briefings in Bioinformatics (in press), Link

* Wen, J., Tian, Y.E., Yang, Z., Cui, Y., Erus, G., Hwang, G., Varol, E., Boquet-Pujadas, A., Chand, G.B. and Nasrallah, I., 2025. Nine Neuroimaging-AI Endophenotypes Unravel Disease Heterogeneity and Partial Overlap across Four Brain Disorders, pp.2023-08. Nature Biomedical Engineering (in press). Link

2024

* Wen, J., Wen, J., Yang, Z., Nasrallah, I.M., Cui, Y., Erus, G., Srinivasan, D., Abdulkadir, A., Mamourian, E., Hwang, G., Singh, A. and Bergman, M., 2024. Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer’s disease continuum. 14(1), p.420.Translational Psychiatry. Link

* Wen, J., Tian, Y.E., Yang, Z., Cui, Y., Anagnostakis, F., Mamourian, E., Zhao, B., Toga, A.W., Zalesky, A. and Davatzikos, C., 2024. 4(9), pp.1290-1307. Nature Aging. Link

* Wen, J., 2024. Multiorgan biological age shows that no organ system is an island. Nature Aging. Link

* Yang, Z., Wen, J. (Co-supervision & Genetic analysis), Erus, G., Govindarajan, S.T., Melhem, R., Mamourian, E., Cui, Y., Srinivasan, D., Abdulkadir, A., Parmpi, P. and Wittfeld, K., 2024. Brain aging patterns in a large and diverse cohort of 49,482 individuals. 30(10), pp.3015-3026. Nature Medicine. Link

* Wen, J., Zhao, B., Yang, Z., Erus, G., Mamourian, E., Cui, Y., Hwang, G., Bao, J., Boquet-Pujadas, A. and Zhou, Z., 2024. The genetic architecture of multimodal human brain age. 15(1), p.2604. Nature Communications. Link

* Wen, J., Antoniades, M., Yang, Z., Hwang, G., Wang, R. and Davatzikos, C., 2024. Dimensional neuroimaging endophenotypes: neurobiological representations of disease heterogeneity through machine learning. Biological Psychiatry. Link

* Yang, Z., Wen, J., (2024). Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering. Nature Communications. Link

* Nasrallah, IM., Abdulkadir, A., Wen, J. (Genetic analysis), Melhem, R., Mamourian, E., Erus, G., Doshi, J., Singh, A., Yang, Z. and Cui, Y., 2024. Genetic and clinical correlates of AI-based brain aging patterns in cognitively unimpaired individuals., 81(5), pp.456-467. JAMA Pyschiatry. Link

2023

* Wen, J., Nasrallah, I.M., Abdulkadir, A., Satterthwaite, T.D., Yang, Z., Erus, G., Robert-Fitzgerald, T., Singh, A., Sotiras, A., Boquet-Pujadas, A. and Mamourian, E., 2023. Genomic loci influence patterns of structural covariance in the human brain, 120(52), p.e2300842120.. Proceedings of the National Academy of Sciences. Link

* Hwang, G., Wen, J. (co-first), Sotardi, S., (2023), Brodkin, E.S., Chand, G.B., Dwyer, D.B., Erus, G., Doshi, J., Singhal, P., Srinivasan, D. and Varol, E., 2023. Assessment of neuroanatomical endophenotypes of autism spectrum disorder and association with characteristics of individuals with schizophrenia and the general population. 80(5), pp.498-507.. JAMA Psychiatry. Link

* Wen, J., Varol, E., Yang, Z., Hwang, G., Dwyer, D., Kazerooni, A.F., Lalousis, P.A. and Davatzikos, C., 2023. Subtyping brain diseases from imaging data. pp.491-510. Machine Learning for Brain Disorders Link

2022

* Wen, J., Fu, C.H., Tosun, D., Veturi, Y., Yang, Z., Abdulkadir, A., Mamourian, E., Srinivasan, D., Skampardoni, I., Singh, A. and Nawani, H., 2022. Characterizing heterogeneity in neuroimaging, cognition, clinical symptoms, and genetics among patients with late-life depression. 79(5), pp.464-474. JAMA Psychiatry, 79(5), pp.464-474. Link

* Wen, J., Varol, E., Sotiras, A., Yang, Z., Chand, G.B., Erus, G., Shou, H., Abdulkadir, A., Hwang, G., Dwyer, D.B. and Pigoni, A., 2022. Multi-scale semi-supervised clustering of brain images: Deriving disease subtypes, 75, p.102304.. Medical Image Analysis, 75, p.102304. Link

* Yang, Z., Wen, J., and Davatzikos, C., (2022). Surreal-GAN: Semi-Supervised Representation Learning via GAN for uncovering heterogeneous disease-related imaging patterns. ICLR. Link

2021

* Wen, J., Samper-González, J., Bottani, S., Routier, A., Burgos, N., Jacquemont, T., Fontanella, S., Durrleman, S., Epelbaum, S., Bertrand, A. and Colliot, O., 2021. Reproducible evaluation of diffusion MRI features for automatic classification of patients with Alzheimer’s disease, 19, pp.57-78.. Neuroinformatics, 19(1), pp.57-78. Link

* Yang, Z., Nasrallah, I.M., Shou, H., Wen, J., Doshi, J., Habes, M., Erus, G., Abdulkadir, A., Resnick, S.M., Albert, M.S. and Maruff, P., 2021. A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure. 12(1), p.7065.. Nature Communications, pp.1-15. Link

2020

* Wen, J., Thibeau-Sutre, E., Diaz-Melo, M., Samper-González, J., Routier, A., Bottani, S., Dormont, D., Durrleman, S., Burgos, N., Colliot, O. and Alzheimer's Disease Neuroimaging Initiative, 2020. Convolutional neural networks for classification of Alzheimer's disease: Overview and reproducible evaluation, 63, p.101694. Medical image analysis, 63, p.101694. Link

* Wen, J., Varol, E., Chand, G., Sotiras, A. and Davatzikos, C., 2020. MAGIC: Multi-scale heterogeneity analysis and clustering for brain diseases. 2020, pp. 678-687. MICCAI. Springer, Cham. Link

2019 and ealier

* Bertrand, A., Wen, J. (co-first), Rinaldi, D., Houot, M., Sayah, S., Camuzat, A., Fournier, C., Fontanella, S., Routier, A., Couratier, P. and Pasquier, F., 2018. Early cognitive, structural, and microstructural changes in presymptomatic C9orf72 carriers younger than 40 years. 75(2), pp.236-245. JAMA neurology, 75(2), pp.236-245. Link

* Wen, J., Zhang, H., Alexander, D.C., Durrleman, S., Routier, A., Rinaldi, D., Houot, M., Couratier, P., Hannequin, D., Pasquier, F. and Zhang, J., 2019. Neurite density is reduced in the presymptomatic phase of C9orf72 disease, 90(4), pp.387-394.. Journal of Neurology, Neurosurgery & Psychiatry 90(4), pp.387-394. Link