MEDICINE (Multi-organ biomEDIcal sCIeNcE) knowledge portal:

MEDICINE is a public knowledge portal for scientific dissemination and data sharing, focusing on our multi-organ research by leveraging AI/ML, imaging, proteomics, metabolomics, and genetics.

GWAS summary statistics & pre-trained AI models

We currently host and make publicly available the GWAS summary statistics and our pre-trained AI models for over 2000 Multi-organ AI-derived Endophenotypes (MAE):

2003 multi-scale brain Patterns of Structural Covariance (PSC) data-driven networks;

84 eye IDPs derived from OCT;

82 heart IDPs derived from heart MRI;

9 PhenoBAGs derived from brain MRI and clinical variables for 9 human organs/systems;

3 brain BAGs derived from multimodal brain MRI;

11 ProtBAGs derived from plasma proteomics;

5 MetBAGs derived from plasma metabolomics;

18 disease dimensions/subtypes for AD, aging, ASD, SCZ, and MDD, derived from brain MRI via (semi)weakly-supervised AI/ML;

2417 raw Olink plasma proteins;

327 NMR raw and composite metabolites;

11 dimensions/subtypes for pan-disease derived from multi-organ imaging data to be released soon...

7 MRIBAGs to be released soon...

Hover your mouse over representative organs on the 3D human anatomy, or click the ORGANS button in the navigation bar to begin exploring!