MUTATE (MUlTi-organ AI endophenoTypE) genetic atlas:

MUTATE is a genetic atlas focusing on delineating the genetic architecture of 2024 multi-organ AI-derived endophenotypes (MAE) derived from UK Biobank.

The GWAS summary data for the 2024 MAEs are publicly available at our two portals:

  • MEDICINE: focusing on multi-organ endophenotypes
  • BRIDGEPORT: focusing on the 2003 brain patterns of structural covariance
  • The GWAS summary data for the 525 disease endopoints (DE) are publicly available at:

  • FinnGen: 521 DEs for diseases of multiple human organ or systems;
  • PGC: 4 brain diseases
  • mutate

    Click the ORGANS button in the navigation bar to start exploring your favorite organ-specific MAEs!