Multimodal Brain PhenoBAG

This is the BAG of the brain defined by the SVR model using t1-weighted, diffusion, and functional MRI data from UK Biobank.

QQ plot

Manhattan plot

Summary Statistics

Data: GWAS summary statistics and pre-trained AI models for brain BAG derived from GM, WM, and FC metrics using UK Biobank brain imaging data.

Citation: Wen, J., Tian, Y.E., et al. The genetic architecture of biological age in nine human organ systems. Nat Aging (2024). https://doi.org/10.1038/s43587-024-00662-8