HYDRA ASD2

This is the dimension/subtype 2 (ASD2) of ASD defined by the HYDRA model using brain imaging data from ABIDE, where ASD2 (schizophrenialike) was characterized by enlarged subcortical volumes, antipsychotic medication use.

QQ plot

Manhattan plot

Summary Statistics

Data: GWAS summary statistics for HYDRA ASD2 derived from brain MRI data using UK Biobank.

Citation: Wen, J., Tian, Y.E., Yang, Z., Cui, Y., Erus, G., Hwang, G., Varol, E., Boquet-Pujadas, A., Chand, G.B. and Nasrallah, I., 2023. Neuroimaging-AI Endophenotypes of Brain Diseases in the General Population: Towards a Dimensional System of Vulnerability. (under revision).