Surreal-GAN Aging5

This is the dimension/subtype 5 (Aging5) of brain aging defined by the Smile-GAN model using brain imaging data from the iSTAGING consortium, where Aging5 shows perisylvian atrophy centered around the insular cortex.

QQ plot

Manhattan plot

Summary Statistics

Data: GWAS summary statistics and pre-trained AI models for Surreal-GAN Aging5 derived from brain MRI data using UK Biobank.