Surreal-GAN Aging5

This is the dimension/subtype 5 (Aging5) of brain aging defined by the Smile-GAN model using brain imaging data from the iSTAGING consortium, where Aging5 shows perisylvian atrophy centered around the insular cortex.

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Manhattan plot

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Summary Statistics

Data: GWAS summary statistics for Surreal-GAN Aging5 derived from brain MRI data using UK Biobank.

  • Citation: Yang, Z., Wen, J. (Co-supervision & Genetic analyses), Erus, G., Melhem, R., Mamourian, E., Cui, Y., Srinivasan, D., Abdulkadir, A., Parmpi, P. and Wittfeld, K., 2023. Brain aging patterns in a large and diverse cohort of 49,482 individuals. Nature Medicine .
  • Citation: Yang, Z., Wen, J. and Davatzikos, C., 2023. Surreal-GAN: Semi-Supervised Representation Learning via GAN for uncovering heterogeneous disease-related imaging patterns. ICLR.
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