Surreal-GAN Aging3

This is the dimension/subtype 3 (Aging3) of brain aging defined by the Surreal-GAN model using brain imaging data from the iSTAGING consortium, where Aging3 indicates the severity of parieto-temporal atrophy, including that in middle temporal gyrus, angular gyrus, and middle occipital gyrus.

QQ plot

Manhattan plot

Summary Statistics

Data: GWAS summary statistics and pre-trained AI models for Surreal-GAN Aging3 derived from brain MRI data using UK Biobank.