MEDICINE (Multi-organ biomEDIcal sCIeNcE) knowledge portal:

MEDICINE is a public knowledge portal for scientific dissemination and data sharing, focusing on our multi-organ research by leveraging AI/ML, imaging, proteomics, metabolomics, and genetics.

GWAS summary statistics & pre-trained AI models

We currently host and make publicly available the GWAS summary statistics and our pre-trained AI models for over 2000 Multi-organ AI-derived Endophenotypes (MAE):

  • 2003 multi-scale brain Patterns of Structural Covariance (PSC) data-driven networks;
  • 12 phenotype-based biological age gaps (BAG) derived from imaging and clinical variables for 9 human organs/systems;
  • 11 proteome-based BAGs derived from plasma proteomics;
  • 5 metabolome-based BAGs derived from plasma metabolomics;
  • 18 disease dimensions/subtypes for AD, aging, ASD, SCZ, and MDD, derived from brain MRI via (semi)weakly-supervised AI/ML;
  • 84 eye IDPs derived from OCT;
  • 82 heart IDPs derived from heart MRI;
  • 11 MAEs for human diseases derived from multi-organ imaging data;
  • >2000 raw Olink plasma proteins to be released soon...
  • 327 NMR metabolites to be released soon...
  • Click the ORGANS button in the navigation bar to start exploring your favorite organ-specific MAEs!

    multiorgan-AI